Marijuana: Can It Kill You?

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"While marijuana may have both short and long term adverse side effects, there is limited research as to whether using it can cause death."
Can Marijuana Kill You?

While marijuana may have both short and long term adverse side effects, there is limited research as to whether using it can cause death. However, smoking weed can impair judgment and motor skills, so smoking cannabis before driving or doing other dangerous activities may increase the risk of an accident. 

Most experts consider the risk of dying from marijuana itself to be very lowTrusted Source.

This does not mean marijuana is a risk-free substance. While many people focus on the beneficial compounds in weed, such as cannabidiol (CBD), there are some possible adverse side effects of weed, especially when using it long term or at a young age.

Has pot killed anyone?

A 2014 study in Forensic Science International reported two cases of sudden death that doctors linked to health complications possibly worsened by marijuana use.

The report indicated that before these deaths, the researchers were not aware of any other deaths related to marijuana use alone. And also concludes that doctors cannot rule out the possibility that pre-existing cardiovascular factors played a role in the deaths.

It is important to note that only after excluding all other causes of death did the report assume the young men experienced fatal cardiovascular events brought on by cannabis.

In 2018, a teenager died of dehydration due to cannabinoid hyperemesis syndrome (CHS). CHS is a condition that can occur in regular cannabis smokers and causes nausea, vomiting, and abdominal pain. 

Despite these incidents, compared to the deaths caused by other drugs, such as alcohol and tobacco, many people consider trusted Source marijuana to be relatively safe.

Health risks of smoking marijuana

Health risks of smoking marijuana
While most experts agree that it is not possible to smoke a lethal dose of marijuana in most cases, this does not mean that it is a harmless substance.

According to the Centers for Disease and Prevention (CDC)Trusted Source, a person is unlikely to die from a marijuana overdose, but this does not mean that there are no risks.

In 2014, Colorado became one of the first states to legalize cannabis for recreational use. Since then, it has seen a significant rise in trusted Sources in the number of emergency room visits related to marijuana use.

A recent report in Missouri MedicineTrusted Source found that some of the more common illnesses connected to marijuana use have also increased in Colorado since legalization. These include:

  • cannabinoid hyperemesis syndrome (CHS)
  • acute psychosis
  • cannabinoid catatonia syndrome
  • acute myopericarditis


Once a rare condition, CHS is becoming increasingly common. A person with CHS experiences severe bouts of vomiting, nausea, abdominal pain, and dehydration from excessive vomiting.

According to Missouri MedicineTrusted Source, it is most common in long term users who smoke cannabis 20 or more times per month.

Many people experiencing CHS say their symptoms go away temporarily after taking a hot bath or showerTrusted Source.

According to an article in Current Drug Abuse ReviewsTrusted Source, some people with CHS find it difficult to accept that marijuana is the source of their symptoms because they understand it to be a cure for nausea and vomiting, rather than the cause of it. However, tetrahydrocannabinol (THC) and other cannabinoids in weed affect both the brain and the digestive tractTrusted Source, along with other areas.

Weed does trigger an antinausea effect on the central nervous system. However, repeated use may dull this effect. THC and other cannabinoids may increase the likelihood of an upset stomach, especially with repeated use.

Treatment for CHS includes therapy, hydration, and antinauseaTrusted Source medication. Other recommendations include stopping using marijuana in any form for a prolonged period of weeks or months trusted Source.

Acute psychosis

Acute psychosis is an alteration of the sense of reality to the point where the person experiences delusions, mood disturbances, and hallucinations. A person experiencing acute psychosis might behave unusually.

A review in Psychiatric Times notes that some evidence suggests a correlation between cannabis use and psychiatric conditions, including cannabis-induced psychosis (CIP).

The review notes a case study of a 19-year-old who experienced an acute psychotic event that was consistent with CIP. The person blamed the pressures of a competitive university environment for their paranoia and isolation, claiming that smoking weed was keeping them sane. The person did, however, receive treatment, stopped smoking cannabis, and experienced no further episodes of psychosis.

Another studyTrusted Source references two reports of people experiencing acute psychotic episodes after using cannabis. In one instance, the only drug in the person's system was cannabis, and the person had no family history of mental health illnesses. In the other case study, the elderly individual ate some marijuana products for the first time and began to display some unusual behavior.

It is possible to deduce that cannabis was the cause of these psychotic episodes, although there is no conclusive evidence.

Treatment for cannabis-induced psychosis includes refraining from using cannabis in any form. In people who are unwilling to do this, doctors may use antipsychotic drugs to protect them from psychosis.

Heart conditions

There is some evidence that marijuana use could lead to cardiovascular issues. A 2001 studyTrusted Source suggests smoking marijuana could be a rare trigger of a heart attack.

There are a few recorded cases of people dying from possibly marijuana-induced complications of an existing medical condition, but these are inconclusive.

However, a recent 25-year longitudinal study trusted Source looked at the risk of cardiovascular events in people with a history of marijuana use. Their research noted that neither total lifetime marijuana use nor recent marijuana use was associated with cardiovascular disease in middle-aged people.

Sometimes, heavy marijuana use may also contribute to acute pericarditisTrusted Source. Pericarditis is inflammation in the pericardium, which is the membrane surrounding the heart.

Some experts believe that changes in the structure of marijuana over recent years may be partly to blame for the increased risk of these conditions.

Most past medical research has used marijuana with relatively low THC content, while in recent years, the THC levels in marijuana have increased significantly, with an increase of about 4% to 12%Trusted Source, on average.

However, a review in Nature Reviews CardiologyTrusted Source noted that the THC content in marijuana has increased over tenfold over the last decade. The review also notes that this increase has led to a rise in the number of severe cardiovascular incidents reported, including:

  • heart attack
  • stroke
  • arrhythmia
  • cardiac arrest

This does not necessarily prove that marijuana causes these events. However, doctors should consider whether a person's use of marijuana is an underlying cause of their cardiovascular problems.

Can weed harm a fetus during pregnancy?

Most doctors will recommend that pregnant women do not smoke any substance because the contents of the smoke may pass to the baby.

A study in Pharmacology & TherapeuticsTrusted Source notes that compounds such as THC readily pass to the placenta. Though the fetus may experience lower levels of THC than the mother, it could still affect them in the long term.

While scientists have not found that cannabis causes physical abnormalities at birth, they have found associations between fetal exposure and changes in physical growth early in life, including low birth weight. Evidence also suggests it has an adverse mental impact on the developing child, including heightening behaviors of anxiety and depression.

Until more research analyzes THC as a potential toxin for fetuses in the womb, researchers suggest pregnant women should not assume that cannabis is safe for them to use.


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VAPEBIZ’s news editor, keep up-to-date with daily news policies regarding Cannabis and Vape. Share some basic knowledge of cannabis, mainly focusing on the daily use of CBD products.

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